NHP Irritable Bowel Syndrome Model Publication
*UPDATED*: Cover art for November 2022 issue (Vol. 4, Issue 11).
Announcing publication of "Regional brain activation during rectal distention and attenuation with alosetron in a nonhuman primate model of irritable bowel syndrome," in FASEB BioAdvances.
Measurement of visceral hypersensitivity associated with IBS using brain activation. Previously DSS-treated macaques exhibited no signs of inflammation on colonoscopy or change in rectal functioning. Potential new model for development of therapeutics for an indication with few treatment options.